Dental CAD/CAM & Dental Prosthesis Market by Type, Size, Growth and Forecast – 2031
Dental CAD/CAM and Dental Prosthesis Market 2022
Persistence Market Research delivers the key insights on the global dental CAD/CAM & dental prosthesis market in its upcoming report titled “Dental CAD/CAM & Dental Prosthesis Market: Global Industry Analysis 2013–2017 and Forecast 2018 – 2026”. In terms of revenue, the global dental CAD/CAM & dental prosthesis market is projected to register a CAGR of 5.6% over the forecast period, owing to various factors, regarding which PMR offers detailed insights and forecast.
The dental CAD/CAM & dental prosthesis market is expected to record a year-over-year growth rate of 5.6% by 2026. The dental CAD/CAM & dental prosthesis market is segmented based on product type, end users and regions. By product type, the dental CAD/CAM & dental prosthesis market is segmented into; dental prosthesis and dental CAD/CAM system.
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Company Profiles
3M
VOC GmbH.
COLTENE Group
DENTSPLY SIRONA INC
Den-Mat Holdings, LLC.
ENVISIONTEC, INC
Ivoclar Vivadent AG
Noble Biocare (Danaher)
Shofu
Dental Wings (Straumann group)
Others.
Dental prosthesis is segmented into custom dental prosthesis which comprises of dental implants, dentures, crowns & bridges, inlays & onlays and others. And 3D Dental Prosthesis which comprises of ceramic based, alloy based and others. Dental CAD/CAM system is segmented into chair-side system and laboratory system. The 3D Dental Prosthesis is expected to account a high share in the dental CAD/CAM & dental prosthesis market, with a growth rate of 5.7% by 2026.
The laboratory system segment is expected to witness sluggish growth in the global dental CAD/CAM & dental prosthesis market due to already penetrated market space.
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The growth of the dental CAD/CAM & dental prosthesis market is related to the dental industry which would benefit a lot from the ongoing production change using digital method. As the technology continues to advance traditional methods, it betters the further improvement in treatments and outcomes coming out of digital manipulation.
3D printing is the most ideal solution which incurs cost that is simply there in other method and ideally helps the entire dental industry to have a cut shot in their spending and with higher production rate and waste control tends the manufacturers to have a better take at generating higher revenue. 3D printing is shifting from prototyping to production
The reach for dental CAD/CAM & dental prosthesis market to match the disposable income of the middle-class population across the globe has led to changing customer approach towards dental treatment.
Products are more furiously accepted in emerging markets as they are cost-effective and offer good quality which suits the present condition and certain points of reimbursements policies for dental CAD/CAM & dental prosthesis which somehow shifts with regional influence marks as a trend that is being followed and visible in emerging regions.
It is an emerging opportunity for manufacturers to provide in-clinic systems to clinics in order to produce dental prosthetics, which is going to save ample time in building a prosthetic, makes the entire process less expensive, provide a more precise finishing and easy working condition. 3D dentistry is well on its verge to become the new standard of dental care.
Most of the dental caries are objective to school going children and is supposedly taken care by the dentists in major high income countries. But the question arises when middle and low income countries are surveyed, a different trend of cases are reported there.
As there is a relative high no. cases in North America and in the European region; the count is somewhere less in Western Pacific and Eastern Mediterranean and for it is less severe in South East Asia and Africa. Also, in Africa, the dentist to population ratio is approx. 1:150,000 against most industrialized countries reported by WHO in 2009
The dental prosthesis segment is estimated to witness significant growth in the global dental CAD/CAM & dental prosthesis market with both custom dental prosthesis and 3D dental prosthesis products available. The 3D dental prosthesis market is most certain to have a higher impact in the overall dental CAD/CAM & dental prosthesis market with products of ceramic based, alloy based and others offered in the segment.
The dental CAD/CAM system is estimated to have a high growth in the global dental CAD/CAM & dental prosthesis market. With chair-side CAD/CAM system expected to have a higher growth rate over the forecast due to its versatility, scalable solution for different indications, speed, productivity, accuracy, repeatability, durability and reduced total cost of operations.
This report assesses the trends that are driving the growth of each segment on the global as well as regional level, and offers potential takeaways that could prove substantially useful for the manufacturers planning to enter the market.
Geographically, the global dental CAD/CAM & dental prosthesis market is segmented into North America, Europe, Latin America, Asia Pacific excluding China and Middle East & Africa.
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This report assesses the trends driving each segment and offers analysis and insights of the dental CAD/CAM & dental prosthesis market in specific regions. Europe is expected to account major share in the global dental CAD/CAM & dental prosthesis market and is expected to grow at a CAGR of 5.8%.
APEC is expected to have the highest growth rate for the global dental CAD/CAM & dental prosthesis market during the forecast period due to growing number of cases and improved healthcare infrastructure.
In this report, we have discussed the individual strategies followed by these companies regarding the improvements in their products, creating new manufacturing facilities, market consolidation and advanced R&D initiatives.
The report has been concluded with key takeaways for players already present in the market and new players planning to enter the dental CAD/CAM & dental prosthesis market.
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Soft Tissue Repair Market 2022 Development Trend, Chain Suppliers, Key Players Analysis and Forecast to 2031
Soft tissue repair is a process of replacement of destroyed or injured tissue by healthy tissue. One of the key factors driving the market is the rise in a number of accidents and accidental injuries. This is leading to the soft tissue injuries in ligaments, muscle, and tendons. Soft tissue injuries are being treated with soft tissue fixation devices and scaffolds. Increasing number of sports injuries is also driving the demand for soft tissue repair. The most common and critical injury among sports people is Traumatic Brain Injury (TBI).
In order to treat TBI, a majority of physicians use tissue scaffolds, this helps in protecting the injured area from a foreign body. The demand for soft tissue repair products is also increasing in the hospitals to deal with the injuries caused due to accidents. With the development of advanced devices, the demand for a minimally invasive procedure is also increasing. This is fueling the growth in the global soft tissue repair market.
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Company Profiles
Braun Melsungen AG
Baxter
C. R. Bard, Inc.
Johnson & Johnson Private Limited
Stryker
Integra LifeSciences Corporation
Medtronic
Acera Surgical, Inc.
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In recent years, the demand for stem cell and tissue engineered products for treating various diseases has also increased. Moreover, companies are investing in the advanced research and development of new soft tissue repair products.
According to the report by Persistence Market Research (PMR), the global soft tissue repair market is expected to witness steady growth during the forecast period 2017-2024. The global market for soft tissue repair is also estimated to bring in more than US$ 7,000 Million revenue by the end of 2024.
Soft Tissue Repair to Witness Largest Application in Orthopedics in the Global Soft Tissue Repair Market
Based on the product type, allograft is likely to witness the highest growth in the global market for soft tissue repair. By the end of the forecast period, allograft is projected to surpass US$ 3,000 Million revenue.
On the basis of application, soft tissue repair is likely to find largest application in orthopedics throughout the forecast period 2017-2024. Orthopedics is estimated to surpass US$ 1,000 Million revenue towards the end of 2024.
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By the end user, hospitals are expected to see a significant growth in the global market for soft tissue repair. By 2024 end, hospitals are estimated to bring in more than US$ 4,000 Million revenue.
North America to Lead the Global Soft Tissue Repair Market
North America is expected to remain dominant in the global market for soft tissue repair in the global market for soft tissue repair. By 2024 end, North America is projected to exceed US$ 3,000 Million revenue.
Presence of advanced healthcare infrastructure and increasing investment by the government in the development of healthcare facilities and advanced treatment methods are some of the factors driving the demand in the soft tissue repair market in the region. Major companies are also conducting research activities to develop devices and products that are technically advanced for soft tissue repair.
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Pharmaceutical Excipients Market 2022, Industry Analysis, Growth Trends, Opportunity and Forecast To 2031
Pharmaceutical Excipients Market 2022
Microcrystalline cellulose (MCC) is one of the most widely used excipients in Europe and Asia Pacific. The prime reasons contributing to MCC’s popularity is its multi-functionality as a diluent used in direct compression and also that it is an anti-caking agent and an emulsifier. Furthermore, it fulfils all USP standards, which further drives its demand.
In addition, manufacture of oral liquid formulations is gaining popularity as a patient-centric drug delivery format, despite having shortcomings such as shorter shelf life and need for airtight packaging. In this context, oral liquid formulation administration is preferred for geriatric and paediatric patients and people suffering from chronic diseases such as cancer with reduced swallowing capacity.
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Key Companies
BASF SE,
Evonik Industries AG,
Innophos Holdings Inc.,
The Lubrizol Corporation,
The Dow Chemical Company,
Wacker Chemie AG and
Ashland Inc.
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Oral liquid formulations provide dosing flexibility, which is particularly suited to oral drugs that are dosed by patient weight or body surface area. However, excipient’s solubility and stability data is extremely important during excipient selection for oral liquid formulations.
These are some of the important findings of the latest report released by Persistence Market Research which is titled as ‘Pharmaceutical Excipients Market: Global Industry Analysis and Forecast 2017 – 2021’. Besides, this report also has a comprehensive section on the market dynamics affecting the global pharmaceutical excipients market and gives a clear picture regarding the factors that are affecting the market growth. As per the numbers provided in this report, the global pharmaceutical excipients market was valued at US$ 5,682.7 Mn in 2017 and is anticipated to reach a valuation of US$ 7,415.2 Mn in 2021 end, displaying a CAGR of 6.9% during the period of assessment 2017-2021.
Global Pharmaceutical Excipients Market: Dynamics
Increasing innovative collaborative research opportunities in pediatric formulations is being pushed through evolution of new regulations, additional funding opportunities, and increased public-private partnerships. This has been shifting focus to development of excipients used in both oral solid and liquid pediatric formulations, which are flexible, dispersible and multi-functional.
Furthermore, continued prioritization of unmet medical needs in pediatrics is expected to drive demand for these excipients and oral formulations in the forthcoming years.
It is also noted that stability testing of excipients is one the most important phases in determining the strength and efficacy of a drug. As more drug manufacturers rely on imports to fulfill requirements for excipients, the stability testing phase adds a layer of complexity to the already costly procedures. This results in uncertainty and lower revenue prospects for excipients manufacturers. These factors are likely to act a hurdle to the market growth of pharmaceutical excipients.
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Global Pharmaceutical Excipients Market: Segmentation and Forecast
Global pharmaceutical excipients market is segmented on the basis of chemistry type, application type, functionality and by region.
Plant-based chemistry type segment has been estimated to witness an increase in market value from US$ 1,650.4 Mn in 2017 to US$ 2,166.8 Mn by 2021.
Oral applications segment is expected to witness a significant gain in market share during the forecast period, 2017-2021. Parenteral dosage forms are expected to witness lower uptake due to dearth of high purity certified excipients.
Binders functionality segment is expected to witness increase in market value from US$ 2,494.2 Mn in 2017 to US$ 3,523.8 Mn by 2021, registering a robust CAGR during the period of assessment.
North America market is expected to remain dominant in terms of production and sales of excipients, accounting for 36.5% of the total pharmaceuticals excipients market value by the end of 2021.
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Remote Patient Monitoring Device Market 2022 Global Key Players, Application, Growth and Analysis – 2031
Remote Patient Monitoring Device Market 2022
Remote patient monitoring is gaining popularity owing to the increase in chronic diseases and aging population. In the traditional healthcare setting all the data collected is lost as soon as the patient leaves the hospital and it is only found when a patient visits again.
However, remote patient monitoring device helps in collecting the data and share it even from a remote location outside hospital or clinic. The concept of telemedicine is also gaining momentum. It allows remote diagnosis and treatment of patients using a telecommunication device, this reduces cost substantially and offers care with comfort.
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Company Profiles
Boston Scientific Corporation
Royal Philips NV
Abbott Laboratories
Nihon Kohten Corporation
F. Hoffmann-La Roche Ltd.
LifeWatch AG
Medtronic
St. Jude Medical
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The manufacturers of remote patient monitoring devices are also focusing on research and development activities and increasingly investing in the same. This is being done to improve the remote patient monitoring device currently offered and also decrease the high cost of devices.
Companies are also looking forward to come-up with a mobile application for remote patient monitoring, thereby, eliminating the need to spend on costly hardware. Manufacturers are developing cardiovascular and respiratory devices with increasing people suffering from various heart and breathing diseases. Hence, portable device monitoring heart rate and blood pressure. Sensor-based devices monitoring oxygen levels and to monitor medication usage are also being provided.
As per the report published by Persistence Market Research, the global remote patient monitoring device is likely to witness a significant growth during the forecast period 2017-2024. The global remote patient monitoring devices market is projected to surpass US$ 1000 Million revenue by the end of 2024.
Cardiac Monitors to Witness the Highest Sales in the Global Market
Based on the product type, cardiac monitors are likely to witness the highest sales during 2017-2024. In terms of value, cardiac monitors are estimated to reach close to US$ 800 Million by 2024 end.
On the basis of indication, cardiac arrhythmia is expected to see a significant growth throughout the forecast period 2017-2024. Cardiac arrhythmia is projected to exceed US$ 300 Million revenue by the end of the forecast period. Meanwhile, ischemic diseases are also likely to see impressive growth in the global market for remote patient monitoring devices.
By the end user, hospitals followed by homecare setting are likely to experience a robust growth during 2017-2024. By the end of 2024, hospitals as the end users are projected to bring in nearly US$ 700 Million revenue.
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North America to Lead the Global Remote Patient Monitoring Devices Market
North America is expected to remain dominant in the global market for remote patient monitoring devices during 2017-2024. By 2024 end, North America is likely to surpass US$ 500 Million in terms of revenue. The U.S. is one of the largest countries in the region for remote patient monitoring devices.
Technological advancements and the growing need for comfort is driving the demand for home-based monitoring devices. According to the report from American Heart Association, more than 80 million Americans have high blood pressure and more than 90 million Americans carry a diagnosis of cardiovascular diseases. Hence, the demand for remote patient monitoring devices is gaining traction in the region.
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Global E Clinical Solution Market and Drivers & Restraints Affecting its Growth; PMR Unleashes the Forecast for 2022-2031
E Clinical Solution Market 2022
According to a new market report published by Persistence Market Research “Global Market Study on E-Clinical Solution Software: Asia to Witness Highest Growth by 2020”, the global e-clinical solution software market was valued at US$ 3,005 Mn in 2014 and is expected to expand at a CAGR of 13.8% from 2014 to 2020, to reach US$ 6,515.3 Mn by 2020.
The global e-clinical solution software market is witnessing significant growth due to increasing clinical trials and R&D investments in pharmaceuticals and life science sectors. Increasing prevalence of diseases across the world is leading to rise in number of clinical trials. Various lifestyle-associated diseases and genetic disorders in the Middle East and North Africa have also led to increase in clinical trials in the respective regions.
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Company Profiles:
Oracle Corporation.
Merge Healthcare Incorporated.
Medidata Solutions Inc.
PAREXEL International Corporation.
BioClinica.
ERT.
OmniComm Systems Inc.
PHT Corporation.
DATATRAK International Inc.
CRF Health Inc.
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In addition, the pharmaceutical industry is facing immense pressure to reduce the time consumed to conduct clinical trials and increase effect of drugs. Presence of various end users such as pharmaceuticals, clinical research organizations (CROs), and healthcare providers has increased the demand for e-clinical solution software. The global e-clinical solution software market was valued at US$ 3,005 Mn in 2014 and is expected to expand at a CAGR of 13.8% from 2014 to 2020 to reach US$ 6,515.3 Mn by 2020.
In North America, the average cost of research and development for a successful pharmaceutical drug continues to increase from pre-clinical stage i.e. initial development stage of drug till FDA approval i.e. launch of the drug in the market. According to Oracle Corporation – an e-clinical software company – the share of global clinical trials conducted in North America has reduced from 30% in 2006 to 19% in 2010.
This was due to complex regulatory and legal frameworks in North America, which led to shifting of the clinical trials market to developing countries such as India and China. This may lead to sluggish growth of clinical trials in the region.
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Countries in Central and Eastern Europe provide abundant opportunities to life science companies for clinical development. According to Oracle Corporation – the percentage of clinical trials conducted in Western Europe has decreased from 25% to 19% and in Eastern Europe; the percentage has increased from 10% to 13% during 2006-2010.
However, Asia has become one of the fastest-growing markets for pharmaceutical products. Improved industry regulatory laws and patent expiration laws in various countries such as Japan, China, and India, have led to the expansion of the clinical trials market in Asia. Cost of conducting clinical trials in Asia is lower compared to that in Europe and the U.S.
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Human Insulin Market 2022 Global Analysis, Opportunities and Forecast To 2031
Human Insulin Market 2022
Incidences of diabetes have risen dramatically over the period of time, and as the global population has grown, so has the demand for insulin. According to Persistence Market Research (PMR), the Global Human Insulin Market would be worth more than US$ 70.68 billion by 2028, witnessing a CAGR of 8% from 2022 to 2028. Extensive research activities in the insulin segments are increasing, as researchers are striving to develop the best molecule for patients’ usage while minimizing adverse effects and enhancing efficiency. The advancements in the insulin segment are expected to fuel market growth in the upcoming period.
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Company Profiles:
Novo Nordisk A/S
Eli Lilly and Company
Sanofi
Biocon
Tonghua Dongbao Pharmaceutical Co., Ltd.
ADOCIA
Wockhardt
Julphar
Merck & Co., Inc.
Pfizer, Inc.
Bristol-Myers Squibb Company
GlaxoSmithKline Plc
Oramed Pharmaceuticals, Inc.
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Diagnostic Imaging Devices Market 2022 Global Analysis, Opportunities and Forecast To 2031
Diagnostic Imaging Devices Market 2022
According to a new market report published by Persistence Market Research “Global Market Study on Diagnostic Imaging Devices: Asia-Pacific to Witness Highest Growth by 2020,” the global diagnostic imaging devices market was valued at USD 26,477.1 million in 2014 and is expected to grow at a CAGR of 5.2% from 2014 to 2020, to reach an estimated value of USD 35,793.4 million in 2020.
The global diagnostic imaging devices market is growing at a moderate rate owing to increasing prevalence of chronic diseases and injuries, and growing aging population. Moreover, factors such as rising initiatives undertaken by government associations to boost awareness of the effects and complications of tuberculosis, cardiovascular diseases, and cancer, and technological advancement and widening application of diagnostic imaging devices are driving the global diagnostic imaging devices market.
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Some of the major players in the diagnostic imaging devices market:
Siemens Healthcare.
Hitachi, Ltd.
Carestream Health, Inc.
Samsung Electronics Co., Ltd.
Toshiba Corporation.
Royal Philips NV
General Electric Company.
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In addition, increasing funding from government bodies is also promoting the use of diagnostic imaging devices in the regions. However, factors such as strict regulatory requirements and heightened risk of cancer owing to exposure to radiation are inhibiting the market growth. The global diagnostic imaging devices market is anticipated to grow from an estimated USD 26,477.1 million in 2014 to USD 35,793.4 million in 2020 at a CAGR of 5.2% during the forecast period.
In North America, growing aging population, increasing health awareness, rising chronic diseases and injuries, large number of ongoing research activities and faster adoption of technologically advanced imaging systems are driving the use of diagnostic imaging devices in the market.
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In Europe, the diagnostic imaging devices market is driven by rising diagnostic requirements due to increasing prevalence of chronic diseases and injuries, and aging population. For instance, according to a paper published on Cancer Incidence and Mortality Pattern in Europe, by International Agency for Research on Cancer in France, approximately, 3.45 million new cases of cancer were diagnosed in Europe in 2012.
However, in Asia-Pacific the growth for diagnostic imaging devices is much higher than developed countries due to growing awareness about benefits of early diagnosis of disease among individuals, large population base, upgradation of health care systems and increasing prevalence of chronic diseases.
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Ultrasonic Skin Care Devices Market 2022, Industry Share, Growth, Demand, Segmentation and Forecast To 2031
Ultrasonic Skin Care Devices Market 2022
Persistence Market Research (PMR) published a report on the ultrasonic skin care devices market, which considers the global industry analysis 2014 – 2018 and opportunity assessment 2019 – 2029, and projects that the ultrasonic skin care devices market is expected to reach ~ US$ 440 Mn by the end of 2019 in terms of value, and is forecasted to reach ~ US$ 720 Mn by the end of 2029.
The presence of large number of companies is creating a healthy environment among the players. Companies with wide range of ultrasonic skin care devices are creating competitive environment for the other players in the market. The players are constantly working on developing better products to stay ahead of the pack.
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Company Profiles:
Merz Pharma GmbH & Co. kGaA
Royal Philips NV
Iskra Medical doo
Ibramed
Shenzhen Leaflife Technology Co., Ltd
Guangzhou Beautylife Electronic Technology Co., Ltd.
Ionto Health & Beauty Gmbh
Grand Aespio Inc.
Thermohealth SL
Adore cosmetics
Hironic Co. Ltd.
Bomtech Electronics co., Ltd
General Project Srl
Asterasys Co. Ltd.
Jellen Products Inc.
Companies such as Merz Pharma GmbH & Co. KGaA, Adore Cosmetics, Jellen Products, Inc. etc. are some of the prominent players in the market. Presence of local players including Shenzhen Bowei tech Co.ltd, Zerone Co., Ltd., and others are further likely to challenge the established companies.
Thus, these conditions are inciting manufacturers to come up with more advanced and improvised ultrasonic skin care devices.
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Manufacturers to Tap Opportunities in Sales through E-commerce Sites
The online availability of the ultrasonic skin care devices has created a favorable condition for the market players. Most of the companies provide the international shipping services, and therefore the devices can be ordered from anywhere globally.
Many products are also available on online shopping sites such as amazon, flipkart, etc. and can be easily purchased by consumers, even in remote areas. These online websites also help in brand promotion and advertisement of ultrasonic skin care devices, thereby creating better opportunities for players.
Increasing Adoption of Home-based Skin Care Devices to Push the Market Growth
There is high demand for home care setting ultrasonic skin care devices which are user friendly and convenient to use. These ultrasonic skin care devices are cost effective and do not require any extra maintenance. Also, the procedure time for home care ultrasonic skin care devices are shorter as compared to table top devices and do not require professionals to operate.
Products such as palm sonic by Adore Cosmetics, Visa boost by Philips, PureCle Dr. by Bomtech Electronics co., Ltd. continue to account major share of the manufacturers’ bottom lines. Home- based devices are easy to handle and do not require any professional assistance. These devices can be used for various applications such as skin tightening and skin rejuvenation, with better results.
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Ultrasonic skin care devices, which use non-invasive ultrasonic energy for the skin tears treatment, have been growing in popularity among consumers. These devices are used for skin tightening, skin rejuvenation, and body contouring applications. Ultrasonic skin care devices are highly preferred due to their better results and long lasting effects.
Table top devices are used in hospitals and clinics, and require professional experts to operate them. The ultrasonic skin care tabletop devices are widely used to overcome several skin related problems and to perform certain procedures like face lifting, skin tightening etc.
However, the cost of these ultrasonic skin care devices are high as compared to other handheld devices, thus representing a threat to the market growth. For instance, Ultherapy ultrasonic device manufactured by Merz Pharma GmbH & Co. KGaA are widely used in aesthetic clinics and has average price of US$ 70000. Such high cost of these devices are likely to act as a hindrance for the growth of the ultrasonic skin care devices market.
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US Animal Drug Compounding Market by Type, Size, Growth and Forecast – 2031
US Animal Drug Compounding Market 2022
The Us Animal Drug Compounding Market is expected to grow on an astounding note shortly. Integrated medical technologies facilitate cloud-based online health records. They thus make way for a well-tuned care plan and invest less time in assimilating pieces of information. This comes through improved workflows and medical IoT. The healthcare vertical would thus go the appropriate remote motoring way shortly.
Persistence Market Research published a report on the animal drug compounding market, which considers the U.S. industry analysis 2014 – 2018 and opportunity assessment 2019 – 2029, and projects that the animal drug compounding market is expected to reach ~ US$ 1 Bn by the end of 2019 in terms of value, and is forecasted to reach ~ US$ 2 Bn by the end of 2029.
Availability of Alternative Dosage Forms Boosting the Demand for Animal Drug Compounding
Commercially available veterinary drugs often come in a single dosage or strength. Animal drug compounding is able to produce desired drugs with alternate dosage and varied dosage forms, which is not possible during the production of branded drugs. Such types of animal drug compounding involve concentrating the drug in the flavoured gel that is generally applied to the paw or fur of the animal, and is administered by licking.
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Company Profiles:
Hoye's Pharmacy
Vertisis Custom Pharmacy
Smith Caldwell Drug Store
Sixth Avenue Medical Pharmacy
Dougherty’s Pharmacy
Triangle Compounding Pharmacy Inc.
Medisca Inc.
Wedgewood Pharmacy
Millers Pharmacy
Also, dosage forms such as transdermal drug delivery in animals, are widely accepted in diverse range of animal drug compounding. To cite an example, anti-parasitic drugs for cattle and anti-flea drugs for dogs and cats are most successful transdermal drug delivery transdermal compounded drug products.
Lower Availability of Generic Substitutes for Veterinary Drugs
Availability of generic substitutes is much lower for veterinary drugs. Most drugs available for animals for critical diseases are branded drugs. Additionally, currently there is no reimbursement available for veterinary drugs, which indicates that most of the drug expense goes out of the pockets of animal owners.
In such circumstances, most pet owners prefer resorting to animal drug compounding that are easily available, cheaper than branded equivalents, and do not require multiple prescriptions.
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CNS Drugs to be Most Frequently Dispensed Extemporaneous Medications from Animal Drug Compounding Pharmacies
Central nervous system inflammation is the most common cause of neurological disorders in dogs and cats. Abnormal limb coordination, seizures, behavioral changes, and blindness are cited as the most common abnormalities in dogs and cats with central nervous system inflammation.
For instance, according to the International Journal of Pharmaceutical Compounding, central nervous system drugs were the most commonly dispensed medications from animal drug compounding pharmacies with approximately 39% of the total veterinary prescriptions.
Absence of Adverse Event Reporting in Animal Drug Compounding
Individual boards of animal drug compounding pharmacies of various states in the U.S. haven’t reported any incidences of adverse events related to animal drug compounding. Furthermore, the U.S. FDA’s adverse drug event reporting system for animals is also not aggregated or comprehensive, and is currently being revised. Since 2001, only 62 compound-related adverse events in animal drug compounding have been reported to the FDA.
No definitive trends can be derived out of them. Therefore, absence of adverse event reporting in animal drug compounding will upsurge the demand for animal drug compounding pharmacies.
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Unsafe Compounding Practices May Deter the Growth of Animal Drug Compounding
The primary factor restraining the usage of animal drug compounding is unsafe compounding practices, which include compounding contaminations and non-adherence to GMP regulations. This is very prominent across sterile compounding involving injectable drugs and intravenous solutions.
Contaminated sterile environments lead to spread of pathogens and fungal infections, and have resulted in various hazards and drug-related deaths, thus dampening the prospects for animal drug compounding. To avoid unsafe animal drug compounding practices, the U.S. FDA has made it mandatory for all outsourcing facilities manufacturing bulk drugs to be inspected and to secure cGMP certification.
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Global Mitotane Market and Drivers & Restraints Affecting its Growth; PMR Unleashes the Forecast for 2022-2031
Mitotane Market 2022
The Mitotane Market is expected to grow step-wise in the next 10 years. Video-calling has penetrated the healthcare vertical, resulting in effective long-distance monitoring. Virtual doctor visits are followed by superlative telemedicine, which results in cost-effectiveness as well as various options to choose from (regarding medical practitioners). This would be how the healthcare vertical go in the upcoming period.
Over the years, mitotane has become one the preferred choices of treatment for Cushing’s syndrome and ACC. The growth of the mitotane market can be attributed to the increased incidence of patient population, which is anticipated to grow significantly in the forecast period.
Furthermore, late recurrence of Cushing’s syndrome and late diagnosis and detection also favours the growth of the mitotane market. ACC has been marked with a high recurrence rate, where treatment using adjuvant therapy has been found to be extremely successful.
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Company Profiles:
HRA Pharma
Bristol-Myers Squibb Company
The ~US$ 12 billion market for mitotane is anticipated to grow at a healthy CAGR over the period of next decade. Macro-economic factors, such increase expenditure in healthcare sector in emerging nations such as China, India, and Brazil is expected to boost the growth of the mitotane market in the forecast period.
With the rise and continual growth in global healthcare expenditure, sales of pharma drugs such as mitotane in countries outside the U.S. represent a potential growth avenue for domestic manufacturers.
According to the World Bank, all regions (except Sub-Saharan Africa) have seen an increase in the healthcare spending as a percentage of total output over the last two decades. Similarly, in 2016, China’s healthcare expenditure grew ~5% of the GDP, which is expected to almost double by 2020.
The market for mitotane is based on two disease indications such as Cushing’s syndrome and ACC. Cushing’s syndrome includes symptoms such as round red face, high blood pressure, weak muscles and bones, abdominal obesity, a fat lump between shoulders, and fragile skin.
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The prevalence rate varies from 10-15 cases/ million population/year. High disease diagnosis screening percentage and attractive reimbursement in developed markets have made the mitotane market to grow significantly.
In contrast, ACC is a rare but aggressive tumour that arises from adrenal cortex and develops late with a large mass. It is estimated that ~600 new cases are diagnosed every year/million population. The disease is most common between 50 and 60 years of age. According to PMR, ACC-based disease indication is anticipated to hold a prominent position in the global mitotane market, in terms of revenue with a global market share of ~60% in 2029.
Major players in the mitotane market are focusing on investing in research and development for the improvement of mitotane with less side effects, and introduction of more affordable and reliable drug treatments in developing regions of the world. Besides, companies are also engaged in commercial partnerships for the sales and marketing of mitotane. Such developments are likely to foster the market to grow in untapped regions and meet the treatment demand.
The mitotane market report offers a comprehensive taxonomy based on the disease indication, distribution channel, and region. Based on disease indication, the global mitotane market is segmented into ACC and Cushing’s syndrome.
Based on distribution channel, the mitotane market is classified into hospital pharmacies, retail pharmacies, online pharmacies, and specialty clinics. With the increase in the incidence of both the diseases and growth opportunities in terms of sales, the mitotane market also offers significant potential for other players to invest in the market.
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The mitotane market has been studied across North America, Latin America, Europe, East Asia, South Asia, Oceania, MEA, and Emerging countries such as China, Brazil, and India. Availability of knowledge-based resources and enhanced research collaboration trends in North America and Europe are estimated to propel the growth of the mitotane market.
North America and Europe markets are projected to be the prominent regional markets for mitotane and are poised to offer substantial opportunities.
Besides, these regions continue to witness high recurrence rate of adrenocortical carcinoma. Use of adjuvant therapy using mitotane has been the prime success factor in the treatment of such indication.
With several collaborations, acquisitions, and agreements between drug industry players and academic institutions are anticipated to help the mitotane market to continually expand and create new dimensions and opportunities for the development of therapeutics for diseases such as ACC and Cushing’s syndrome.
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Persistence Market Research is here to provide companies a one-stop solution with regards to bettering customer experience. It does engage in gathering appropriate feedback after getting through personalized customer interactions for adding value to customers’ experience by acting as the “missing” link between “customer relationships” and “business outcomes’. The best possible returns are assured therein.
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Persistence Market Research
Address – 305 Broadway, 7th FloorNew York City,
NY 10007 United States
U.S. Ph. – +1-646-568-7751
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